Description

5-Fluoro-L-(2-Furanidinyl)-4-(Trimethylsilyloxy)-2-Pyrimidone is a specialized, high-value pyrimidone derivative featuring a unique trifunctional structure. This compound is critical for advanced pharmaceutical research and development, particularly in the synthesis of novel nucleoside analogs and antiviral agents. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of experimental antiviral and anticancer nucleoside analogs.
• Protease Inhibitor Research: Used in the development of protease inhibitors for treating viral infections like HIV and HCV.
• Nucleoside Chemistry: Serves as a protected or modified nucleoside precursor in oligonucleotide and prodrug synthesis.
• Chemical Biology Probes: Utilized in the creation of labeled or tagged compounds for studying enzyme mechanisms and cellular processes.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of active pharmaceutical ingredients (APIs).
• Academic Research: A valuable reagent for universities and research institutes exploring novel heterocyclic chemistry and medicinal chemistry.

Basic Information

Product Name	5-Fluoro-L-(2-Furanidinyl)-4-(Trimethylsilyloxy)-2-Pyrimidone
CAS No.	79107-96-3
Molecular Formula	C13H18FN3O3Si
Molecular Weight	311.39 g/mol
Synonyms	4-(Trimethylsilyloxy)-5-fluoro-2-pyrimidinone L-Furanidinyl Derivative; 5-Fluoro-4-(trimethylsiloxy)-2(1H)-pyrimidinone, 1-(2,5-dihydro-2-furanyl)-; 1-(2,5-Dihydro-2-furanyl)-5-fluoro-4-(trimethylsiloxy)-2(1H)-pyrimidinone; 5-Fluoro-1-(2,5-dihydrofuran-2-yl)-4-((trimethylsilyl)oxy)pyrimidin-2(1H)-one; L-Furanidinyl-5-fluoro-4-TMS-oxypyrimidone; 79107-96-3; FCAS 79107-96-3
EINECS	Contact for details

Quality Control

Every batch of 5-Fluoro-L-(2-Furanidinyl)-4-(Trimethylsilyloxy)-2-Pyrimidone is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural integrity suitable for sensitive research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and compliance with your internal standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under a dry inert atmosphere (e.g., nitrogen or argon) when opening the primary container to prevent degradation. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.