Description

3-(Piperidin-4-Yl)-3,4-Dihydroquinazolin-2(1H)-One is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily sought by pharmaceutical R&D departments, contract research organizations (CROs), and fine chemical manufacturers engaged in developing next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting neurological disorders.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery.
• API Development: Serves as a building block for the final chemical steps in producing investigational new drugs, especially kinase inhibitors or receptor modulators.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and cGMP production.
• Biochemical Tool Compound: May be utilized in vitro to study biological pathways and protein interactions.

Basic Information

Product Name	3-(Piperidin-4-Yl)-3,4-Dihydroquinazolin-2(1H)-One
CAS No.	79098-75-2
Molecular Formula	C₁₃H₁₇N₃O
Molecular Weight	231.29 g/mol
Synonyms	2(1H)-Quinazolinone, 3,4-dihydro-3-(4-piperidinyl)-; 3-(4-Piperidinyl)-3,4-dihydro-2(1H)-quinazolinone; 3-(Piperidin-4-yl)-1,2,3,4-tetrahydroquinazolin-2-one; 3,4-Dihydro-3-(4-piperidinyl)-2(1H)-quinazolinone; Quinazolin-2(1H)-one, 3,4-dihydro-3-(4-piperidinyl)-; 79098-75-2; 3-(Piperidin-4-yl)-3,4-dihydroquinazolin-2(1H)-one
EINECS	Contact for details

Quality Control

Our production of 3-(Piperidin-4-Yl)-3,4-Dihydroquinazolin-2(1H)-One adheres to stringent internal quality standards, ensuring batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support development projects requiring material produced under cGMP guidelines and can provide documentation to meet regulatory submission requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.