Description

5-Bromo-4-Chloro-2-Methanesulfonyl-Pyrimidine is a high-purity, multi-functional pyrimidine derivative serving as a critical building block in advanced organic synthesis. Its unique halogenated and sulfonated structure makes it an invaluable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of nucleoside analogs, kinase inhibitors, and other small-molecule drug candidates.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Chemical Research & Development: Serves as a versatile scaffold for exploring new chemical entities and reaction pathways in medicinal chemistry.
• Material Science: Potential building block for creating functionalized polymers or organic electronic materials.
• Cross-Coupling Reactions: The bromo and chloro substituents make it a suitable substrate for Suzuki, Stille, and other palladium-catalyzed coupling reactions.

Basic Information

Product Name	5-Bromo-4-Chloro-2-Methanesulfonyl-Pyrimidine
CAS No.	79091-24-0
Molecular Formula	C5H3BrClN2O2S
Molecular Weight	287.51 g/mol
Synonyms	2-Methanesulfonyl-5-bromo-4-chloropyrimidine; 5-Bromo-4-chloro-2-(methylsulfonyl)pyrimidine; 4-Chloro-5-bromo-2-methanesulfonylpyrimidine; 79091-24-0; 5-Bromo-4-chloro-2-(methylsulfonyl)pyrimidine; 5-Bromo-4-chloro-2-mesylpyrimidine; 4-Chloro-5-bromo-2-(methylsulfonyl)pyrimidine
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Chloro-2-Methanesulfonyl-Pyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to support your R&D and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. The compound may be moisture-sensitive; handle and store under inert atmosphere if prolonged storage is required.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.