Description

Somatostatin, Cyclo(Des-Ala(1)-Des-Gly(2)-S-Come-Homo-Cysnh2(3)-Trp(8)-Des-Cys(14))- CAS NO 78841-24-4 is a synthetic cyclic peptide analog of the endogenous hormone somatostatin, engineered for enhanced metabolic stability and receptor selectivity. This compound is of significant value in pharmaceutical research and development as a potent tool for studying neuroendocrine regulation and developing targeted therapies. It is primarily needed by biotech companies, academic research institutions, and pharmaceutical manufacturers engaged in endocrinology, oncology, and metabolic disease research.

Application

• Biochemical Research: Used as a reference standard and pharmacological tool in studies of somatostatin receptor (SSTR) subtypes, particularly SSTR2 and SSTR5.
• Drug Discovery: Serves as a key intermediate or lead compound in the development of novel peptide-based therapeutics for acromegaly, neuroendocrine tumors, and diabetic retinopathy.
• In Vitro Diagnostics: Employed in the development and calibration of immunoassays (e.g., ELISA, RIA) for somatostatin and related peptide detection.
• Signal Transduction Studies: Utilized to investigate G-protein coupled receptor (GPCR) signaling pathways and adenylate cyclase inhibition in cellular models.
• Metabolic Research: Applied in experimental models to study the inhibition of growth hormone, insulin, and glucagon secretion.
• Neuroscience: Acts as a modulator in research on neurotransmitter release and neuronal excitability within the central and peripheral nervous systems.

Basic Information

Product Name	Somatostatin, Cyclo(Des-Ala(1)-Des-Gly(2)-S-Come-Homo-Cysnh2(3)-Trp(8)-Des-Cys(14))- CAS NO 78841-24-4
CAS No.	78841-24-4
Molecular Formula	C68H88N18O19S2
Molecular Weight	1509.66 g/mol
Synonyms	Cyclo(des-Ala1-des-Gly2-S-Come-Homo-Cys-NH23-Trp8-des-Cys14)-Somatostatin; Des-AA1,2,14-[Cys3(S-Come-Homo),Trp8]-Somatostatin; Somatostatin Cyclic Analog; BIM-23056; DC-23-056; Cyclic Somatostatin Derivative; SSTR2/5 Selective Analog
EINECS	Contact for details

Quality Control

Our high-purity peptide is manufactured under controlled conditions to ensure batch-to-batch consistency. Quality is assured through rigorous analytical testing including HPLC, MS, and amino acid analysis. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent moisture uptake. For long-term storage, keep under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to theoretical mass
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 8.0%
Peptide Content	≥ 80.0%
Acetate Content (HPLC)	≤ 15.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.