Description

n-(2-Aminoethyl)-3,7,12-Trihydroxycholan-24-Amide is a chemically modified bile acid derivative, synthesized by conjugating a primary amine group to the cholanic acid backbone. This structural modification imparts unique amphiphilic and biochemical properties, making it a valuable intermediate for advanced research and pharmaceutical development. It is primarily sought by professionals in the life sciences sector for its role in drug discovery, biochemical conjugation, and as a building block for specialized surfactants or diagnostic agents.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of targeted drug conjugates and novel therapeutic agents.
• Biochemical Research: Used as a derivatization agent or a model compound in studies of bile acid transport, metabolism, and receptor interactions.
• Diagnostic Agent Synthesis: Employed in the development of contrast agents or probes for medical imaging due to its modifiable structure.
• Specialty Surfactant Production: Acts as a building block for synthesizing high-value, biocompatible surfactants with specific micellar properties.
• Conjugation Chemistry: The primary amine group enables its use in coupling reactions for labeling proteins, peptides, or other biomolecules.

Basic Information

Product Name	n-(2-Aminoethyl)-3,7,12-Trihydroxycholan-24-Amide
CAS No.	78793-09-6
Molecular Formula	C₂₆H₄₆N₂O₅
Molecular Weight	466.66 g/mol
Synonyms	3α,7α,12α-Trihydroxy-5β-cholan-24-oyl ethylenediamine; Taurocholic Acid Amide Derivative; Cholylglycine Ethylenediamine Amide; N-(2-Aminoethyl)-3α,7α,12α-trihydroxy-5β-cholan-24-amide; 5β-Cholan-24-amide, N-(2-aminoethyl)-3α,7α,12α-trihydroxy-; Ethylenediamine Cholamide; Taurochenodeoxycholic Acid Amide Analog
EINECS	Contact for details

Quality Control

Our n-(2-Aminoethyl)-3,7,12-Trihydroxycholan-24-Amide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.