Description

Prothrombin Fragment 2 is a defined polypeptide fragment derived from the blood coagulation factor prothrombin. This high-purity biochemical is essential for advanced research and development in the fields of hemostasis and thrombosis. It serves as a critical reagent for scientists and manufacturers developing diagnostic assays, studying coagulation pathways, and investigating novel therapeutic targets. The product is supplied under stringent quality control to ensure batch-to-batch consistency for reliable experimental and production outcomes.

Application

• Coagulation Research: Used as a standard or substrate in biochemical studies to investigate the intrinsic and extrinsic pathways of blood clotting.
• Diagnostic Assay Development: A key component in the calibration and validation of clinical diagnostic kits for measuring prothrombin time (PT) and other coagulation factors.
• Pharmaceutical R&D: Employed in screening and characterizing potential anticoagulant or procoagulant drug candidates.
• Enzyme Kinetics Studies: Serves as a specific substrate for thrombin and other serine proteases involved in the coagulation cascade.
• Quality Control Reagent: Used in biopharmaceutical manufacturing as a reference material to ensure the potency and consistency of related therapeutic products.
• Antibody Production: Acts as an immunogen for generating specific antibodies used in immunoassays and immunohistochemistry.

Basic Information

Product Name	Prothrombin Fragment 2
CAS No.	78768-79-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Prothrombin Fragment F2; Activation Fragment 2; Prothrombin Fragment 1+2; FII Fragment 2; Coagulation Factor II Fragment 2; Prothrombin Activation Peptide; Thrombin Fragment Precursor
EINECS	Contact for details

Quality Control

Our Prothrombin Fragment 2 is manufactured and tested to meet exacting standards for research and in-vitro diagnostic use. Each batch undergoes rigorous analytical characterization, including purity assessment by HPLC and identity confirmation. We provide comprehensive Certificates of Analysis (COA) detailing all quality parameters, ensuring full traceability and compliance with your application requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Biological Activity	Assessed by functional assay
Endotoxin	< 1.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.