Description

3-(4-Trifluoromethyl-Phenoxy)-Phenylamine is a specialized aromatic amine intermediate featuring a trifluoromethylphenoxy substituent. This compound matters for its role as a key building block in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where the trifluoromethyl group imparts desirable properties like enhanced metabolic stability and lipophilicity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with optimized performance characteristics.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the trifluoromethyl group can improve biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a building block for electron-transport materials and charge-transport layers in display and lighting technologies.
• Polymer Modification: Incorporated into polymer backbones to create high-performance, specialty polymers with unique thermal and chemical resistance properties.
• Dye & Pigment Manufacturing: Acts as an intermediate for producing complex, high-value dyes and organic pigments.
• Research & Development: Employed in academic and industrial labs for methodological studies and the discovery of new chemical entities.

Basic Information

Product Name	3-(4-Trifluoromethyl-Phenoxy)-Phenylamine
CAS No.	78748-23-9
Molecular Formula	C13H10F3NO
Molecular Weight	253.22 g/mol
Synonyms	3-(4-(Trifluoromethyl)phenoxy)aniline; 3-(4-Trifluoromethylphenoxy)aniline; 3-Amino-4'-(trifluoromethyl)diphenyl ether; 3-Phenoxy-4-(trifluoromethyl)aniline; Benzenamine, 3-[4-(trifluoromethyl)phenoxy]-; 78748-23-9; 4'-(Trifluoromethyl)-3-aminodiphenyl ether
EINECS	Contact for details

Quality Control

Our 3-(4-Trifluoromethyl-Phenoxy)-Phenylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in darkness.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.