Description

1H-Purine-2,6-Dione, 3,7-Dihydro-1,3-Dimethyl-7-(3-(Dimethylamino)-2-Hydroxypropyl)-8-((Phenylmethyl)Amino)-, Monohydrochloride is a high-purity, chemically defined active pharmaceutical ingredient (API) and key intermediate. This compound is critical for ensuring the efficacy and consistency of advanced pharmaceutical formulations, particularly in specialized therapeutic areas. It is primarily required by pharmaceutical R&D laboratories, fine chemical manufacturers, and contract development and manufacturing organizations (CDMOs) engaged in the synthesis of complex drug molecules.

Application

• Pharmaceutical Active Ingredient (API): Serves as a core structural component in the synthesis of specific therapeutic agents.
• Research & Development: Used as a critical reference standard and building block in medicinal chemistry for developing new drug candidates.
• Process Chemistry & Scale-Up: Employed as a key intermediate in the pilot and commercial-scale manufacturing of target pharmaceuticals.
• Biochemical Research: Utilized in studies investigating purine-based biological pathways and receptor interactions.
• Contract Manufacturing: Supplied to CDMOs for the production of client-specific novel compounds and generics.
• Analytical Standard: Provides a high-purity standard for quality control (QC) and analytical method development (e.g., HPLC, LC-MS).

Basic Information

Product Name	1H-Purine-2,6-Dione, 3,7-Dihydro-1,3-Dimethyl-7-(3-(Dimethylamino)-2-Hydroxypropyl)-8-((Phenylmethyl)Amino)-, Monohydrochloride
CAS No.	78721-04-7
Molecular Formula	C19H29ClN6O3
Molecular Weight	424.93 g/mol
Synonyms	8-(Benzylamino)-7-[3-(dimethylamino)-2-hydroxypropyl]-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione monohydrochloride; 8-(Benzylamino)theophylline Propanoic Acid Derivative Hydrochloride; 7-[3-(Dimethylamino)-2-hydroxypropyl]-8-[(phenylmethyl)amino]-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione hydrochloride; 8-Benzylaminotheophylline Propanoic Acid Derivative HCl; Theophylline-8-(benzylamino)-7-(3-dimethylamino-2-hydroxypropyl) Hydrochloride; 1,3-Dimethyl-8-(benzylamino)-7-(3-dimethylamino-2-hydroxypropyl)xanthine Hydrochloride
EINECS	Contact for details

Quality Control

Our 1H-Purine-2,6-Dione, 3,7-Dihydro-1,3-Dimethyl-7-(3-(Dimethylamino)-2-Hydroxypropyl)-8-((Phenylmethyl)Amino)-, Monohydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis to ensure it meets stringent specifications for pharmaceutical use. Certificates of Analysis (COA) documenting all test results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.