Description

Ozagrel is a potent and selective thromboxane A2 (TXA2) synthase inhibitor, a key pharmaceutical intermediate and active pharmaceutical ingredient (API). Its primary value lies in its ability to prevent platelet aggregation and vasoconstriction, making it a critical component in the development of anti-thrombotic and cerebrovascular therapeutics. This compound is essential for pharmaceutical manufacturers and research institutions focused on cardiovascular and neurological drug development, particularly in markets producing medications for ischemic stroke and related conditions.

Application

• As a key Active Pharmaceutical Ingredient (API) in the manufacture of antiplatelet and antithrombotic medications.
• Primary intermediate in the synthesis of drugs targeting cerebrovascular diseases, such as treatments for acute ischemic stroke.
• Used in pharmaceutical research and development for novel therapeutics aimed at TXA2 pathway inhibition.
• Critical material for the production of finished dosage forms, including tablets and injectables, in cGMP facilities.
• Reference standard for analytical testing and quality control in pharmaceutical laboratories.
• Starting material for process chemistry and scale-up synthesis of related thromboxane synthase inhibitors.

Basic Information

Product Name	Ozagrel
CAS No.	78712-80-8
Molecular Formula	C13H12N2O2
Molecular Weight	228.25 g/mol
Synonyms	Ozagrel; (E)-3-[4-(1H-Imidazol-1-ylmethyl)phenyl]-2-propenoic Acid; OKY-046; (E)-3-[p-(1H-Imidazol-1-ylmethyl)phenyl]acrylic Acid; Cataclot; Xanbon; Thromboxane A2 Synthase Inhibitor OKY-046; 4-[(1H-Imidazol-1-yl)methyl]cinnamic Acid
EINECS	Contact for details

Quality Control

Our Ozagrel is manufactured under strict quality management systems to ensure it meets the high-purity standards required for pharmaceutical applications. Each batch is subjected to comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling via advanced techniques like HPLC. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.