Description

Ozagrel is a potent and selective thromboxane A2 (TXA2) synthase inhibitor, a key compound in the development of antiplatelet and antithrombotic agents. Its primary value lies in its ability to effectively prevent platelet aggregation and vasoconstriction, making it a critical intermediate for advanced pharmaceutical research and development. This product is essential for pharmaceutical manufacturers, R&D laboratories, and academic institutions focused on developing treatments for cardiovascular and cerebrovascular diseases, such as ischemic stroke and thrombosis.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of advanced antiplatelet and antithrombotic drug candidates.
• Cardiovascular Research: Used in preclinical and clinical research to study the inhibition of thromboxane A2 synthase and its effects on platelet function.
• Cerebrovascular Disease Studies: Applied in the development of therapeutic agents targeting ischemic stroke and related conditions.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Biochemical Research: Employed in studies investigating the arachidonic acid pathway and eicosanoid biosynthesis.
• API Synthesis: A critical starting material or intermediate in the commercial-scale production of active pharmaceutical ingredients (APIs) for antiplatelet therapies.

Basic Information

Product Name	Ozagrel
CAS No.	78712-45-5
Molecular Formula	C13H12N2O2
Molecular Weight	228.25 g/mol
Synonyms	Ozagrel; (E)-3-[4-(1H-Imidazol-1-ylmethyl)phenyl]-2-propenoic Acid; OKY-046; (E)-3-[p-(1H-Imidazol-1-ylmethyl)phenyl]acrylic Acid; 4-[(1H-Imidazol-1-yl)methyl]cinnamic Acid; cis-Ozagrel; Thromboxane A2 Synthase Inhibitor OKY-046
EINECS	Contact for details

Quality Control

Our Ozagrel is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and stringent control of residual solvents and impurities to ensure it meets high-grade standards for pharmaceutical research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5% Any single unknown impurity ≤0.5%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.