Description

Ozagrel is a potent and selective thromboxane A2 (TXA2) synthase inhibitor, a key compound in the development of antiplatelet and antithrombotic agents. Its primary value lies in its ability to effectively prevent the formation of thromboxane A2, a prostanoid that promotes platelet aggregation and vasoconstriction. This makes Ozagrel CAS NO 78712-44-4 a critical intermediate and active pharmaceutical ingredient (API) for researchers and manufacturers developing treatments for cardiovascular and cerebrovascular diseases, such as the prevention of cerebral infarction and the improvement of ischemic symptoms.

Application

• Active Pharmaceutical Ingredient (API): Primary use as the key therapeutic agent in finished pharmaceutical formulations.
• Antiplatelet Drug Development: Core component in R&D for medications aimed at preventing abnormal blood clot formation.
• Cerebrovascular Disease Treatment: Used in drugs for conditions like cerebral thrombosis and to alleviate symptoms following ischemic stroke.
• Thromboxane A2 Synthase Inhibition Research: Essential reference standard and tool compound for biochemical and pharmacological studies.
• Pharmaceutical Intermediate: Serves as a high-purity building block in the synthesis of more complex drug molecules.
• Clinical Research Materials: Supplied to academic and institutional laboratories for preclinical and clinical trial studies.

Basic Information

Product Name	Ozagrel
CAS No.	78712-44-4
Molecular Formula	C13H12N2O2
Molecular Weight	228.25 g/mol
Synonyms	(E)-3-[4-(1H-Imidazol-1-ylmethyl)phenyl]-2-propenoic acid; OKY-046; Cataclot; Xanbon; (2E)-3-[4-(Imidazol-1-ylmethyl)phenyl]prop-2-enoic acid; Ozagrel Hydrochloride (salt form); Thromboxane A2 Synthase Inhibitor OKY-046; 4-[(1H-Imidazol-1-yl)methyl]cinnamic acid
EINECS	Contact for details

Quality Control

Our Ozagrel is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide material that meets stringent specifications suitable for pharmaceutical R&D and manufacturing. Comprehensive testing includes identity, assay, and impurity profile analysis via advanced chromatographic methods. A Certificate of Analysis (COA) documenting all release tests is available for every batch to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time conforms to reference standard
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5% Any single unknown impurity ≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.