Description

Ozagrel Hydrochloride is a potent and selective thromboxane A2 (TXA2) synthase inhibitor, playing a critical role in modulating platelet aggregation and vasoconstriction pathways. Its primary value lies in its application as a key pharmaceutical intermediate or active pharmaceutical ingredient (API) in the development of anti-thrombotic and cerebrovascular medications. This compound is essential for manufacturers and research institutions in the global pharmaceutical and life sciences sectors focused on cardiovascular and neurological therapeutics. The material is supplied as a high-purity solid, requiring specific handling due to its sensitive nature.

Application

• Primary use as an Active Pharmaceutical Ingredient (API) in antiplatelet medications.
• Critical intermediate in the synthesis of advanced thromboxane A2 synthase inhibitors.
• Research and development of novel therapeutics for cerebrovascular disorders such as cerebral infarction.
• Development of treatments for asthma and allergic diseases, leveraging its role in eicosanoid metabolism.
• Biochemical research tool for studying platelet aggregation and related vascular mechanisms.
• Potential use in veterinary pharmaceuticals for cardiovascular applications.

Basic Information

Product Name	Ozagrel Hydrochloride
CAS No.	78712-43-3
Molecular Formula	C13H12N2O2•HCl
Molecular Weight	272.71 g/mol
Synonyms	Ozagrel HCl; (E)-3-[4-(1H-Imidazol-1-ylmethyl)phenyl]-2-propenoic acid hydrochloride; OKY-046 Hydrochloride; Cataclot; Xanbon; 4-[(1H-Imidazol-1-yl)methyl]cinnamic acid hydrochloride; (E)-4-(Imidazol-1-ylmethyl)cinnamic acid hydrochloride
EINECS	Contact for details

Quality Control

Our Ozagrel Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identification by IR and NMR spectroscopy, and tests for residual solvents and related substances, to ensure it meets high-grade pharmaceutical standards. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.