Description

2-Fluoro-L-Tyrosine is a fluorinated derivative of the essential amino acid L-tyrosine, serving as a crucial building block in advanced biochemical research and pharmaceutical development. Its primary value lies in its role as a non-natural amino acid for the synthesis of peptides and proteins, where the fluorine atom acts as a probe or modulator of biological activity. This compound is essential for researchers and manufacturers in pharmaceutical R&D, proteomics, and radiopharmaceutical chemistry, particularly in the development of PET (Positron Emission Tomography) tracers and enzyme inhibitors.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates and enzyme inhibitors targeting tyrosine kinase pathways.
• PET Tracer Development: Used in radiochemistry for labeling with fluorine-18 (18F) to create diagnostic imaging agents for oncology and neurology.
• Biochemical Research: Incorporation into peptides and proteins to study structure-activity relationships (SAR), protein folding, and enzyme mechanisms via 19F NMR spectroscopy.
• Proteomics & Labeling: Acts as a stable, non-radioactive label in mass spectrometry-based proteomic studies for tracking and quantification.
• Academic & Industrial R&D: Fundamental research tool in medicinal chemistry and chemical biology for exploring new therapeutic modalities.

Basic Information

Product Name	2-Fluoro-L-Tyrosine
CAS No.	78709-81-6
Molecular Formula	C9H10FNO3
Molecular Weight	199.18 g/mol
Synonyms	(S)-2-Amino-3-(2-fluoro-4-hydroxyphenyl)propanoic acid; L-2-Fluorotyrosine; (2S)-2-Amino-3-(2-fluoro-4-hydroxyphenyl)propanoic acid; 2-F-Tyr; 2-Fluoro-4-hydroxy-L-phenylalanine; F-Tyr-OH; 2-Fluoro-L-tyrosine; 2-Fluorotyrosine
EINECS	Contact for details

Quality Control

Our 2-Fluoro-L-Tyrosine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.