Description

Dynorphin A, Fragment 1-8 is a specific bioactive peptide fragment derived from the endogenous opioid peptide Dynorphin A. This compound is of significant interest for its role as a potent and selective κ-opioid receptor (KOR) agonist, making it a critical tool for neurological and pharmacological research. It is essential for researchers and developers in neuroscience, pain management, and drug discovery who require high-purity reference standards and biochemical reagents.

Application

• Neuroscience Research: Used as a selective ligand to study the structure, function, and signaling pathways of κ-opioid receptors (KOR) in the central nervous system.
• Pharmacological Studies: Serves as a reference standard in assays to screen and evaluate novel analgesic compounds and their mechanisms of action.
• Biochemical Reagent: Employed in cell-based assays and receptor binding studies to investigate neuropeptide interactions and cellular responses.
• Drug Discovery & Development: Acts as a key biochemical tool in the research and development of new therapeutics targeting pain, addiction, and mood disorders.
• Academic & Institutional Research: Provides a reliable standard for universities and research institutes conducting fundamental studies on opioid systems.

Basic Information

Product Name	Dynorphin A, Fragment 1-8
CAS No.	78658-38-5
Molecular Formula	C44H62N12O10
Molecular Weight	918.0 g/mol
Synonyms	Dynorphin A (1-8); [Des-Tyr1]-Dynorphin A; Dynorphin A 1-8 amide; Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile; YGGFLRRI-NH2; Dynorphin A (1-8) amide; Opioid peptide fragment
EINECS	Contact for details

Quality Control

Our Dynorphin A, Fragment 1-8 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and MS for identity confirmation, to ensure it meets the high standards required for research applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Solubility	Soluble in water, acetic acid, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.