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2-Amino-4,6-Di(tert-Butyl)Pyrimidine CAS NO 78641-13-1
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CAS No.:78641-13-1
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2-Amino-4,6-Di(tert-Butyl)Pyrimidine is a sterically hindered pyrimidine derivative characterized by its bulky tert-butyl substituents. This molecular structure is crucial for its role as a high-performance intermediate and ligand in advanced chemical synthesis. It is primarily utilized by R&D chemists and process engineers in the pharmaceutical and specialty chemical industries for applications requiring selective reactivity and stability. The compound's unique properties make it valuable for developing catalysts and active pharmaceutical ingredients (APIs).
Application
- Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those requiring sterically hindered nitrogen heterocycles.
- Catalyst Ligand: Used in the development of transition metal catalysts for asymmetric synthesis and cross-coupling reactions due to its electron-donating and bulky properties.
- Agrochemical Research: Employed as a precursor in the development of new herbicides and fungicides with specific modes of action.
- Material Science: Acts as a monomer or additive in the synthesis of specialty polymers and advanced organic materials.
- Chemical Synthesis: Functions as a versatile reagent for constructing complex pyrimidine-based structures in academic and industrial research.
Basic Information
| Product Name | 2-Amino-4,6-Di(tert-Butyl)Pyrimidine |
| CAS No. | 78641-13-1 |
| Molecular Formula | C12H21N3 |
| Molecular Weight | 207.32 g/mol |
| Synonyms | 2-Amino-4,6-bis(tert-butyl)pyrimidine; 4,6-Di-tert-butyl-2-pyrimidinamine; 2-Pyrimidinamine, 4,6-bis(1,1-dimethylethyl)-; 4,6-Di-tert-butylpyrimidin-2-amine; 2-Amino-4,6-di-t-butylpyrimidine; DTBP; 2-ADTBP |
| EINECS | Contact for details |
Quality Control
Our 2-Amino-4,6-Di(tert-Butyl)Pyrimidine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles. We adhere to cGMP principles where applicable to support our customers in regulated industries.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials such as strong oxidizing agents.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Melting Point | Contact for details |
| Loss on Drying | ≤ 1.0% |
| Residue on Ignition | ≤ 0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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