Description

Ethyl 7-(Pyridin-2-Yl)Pyrazolo[1,5-A]Pyrimidine-3-Carboxylate is a high-purity, synthetically valuable heterocyclic building block. This compound is essential for advanced pharmaceutical research and development, serving as a key intermediate in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of potential drug candidates targeting various diseases.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its privileged pyrazolopyrimidine scaffold.
• Kinase Inhibitor Development: Serves as a core structure in the research and development of kinase inhibitors, a major class of therapeutics.
• Agrochemical Synthesis: Employed as an intermediate in the creation of novel crop protection agents and pesticides.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	Ethyl 7-(Pyridin-2-Yl)Pyrazolo[1,5-A]Pyrimidine-3-Carboxylate
CAS No.	78562-50-2
Molecular Formula	C14H12N4O2
Molecular Weight	268.27 g/mol
Synonyms	Ethyl 7-(2-Pyridinyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate; 7-(Pyridin-2-yl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid ethyl ester; Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid, 7-(2-pyridinyl)-, ethyl ester; Ethyl 7-(2-pyridyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate; 78562-50-2; SCHEMBL11806279; ZINC000253899793
EINECS	Contact for details

Quality Control

Our Ethyl 7-(Pyridin-2-Yl)Pyrazolo[1,5-A]Pyrimidine-3-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of pharmaceutical R&D and cGMP standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.