Description

Fmoc-Asp(Otbu)-Osu CAS NO 78553-23-8 is a high-purity, protected amino acid derivative specifically designed for solid-phase peptide synthesis (SPPS). This compound is a critical building block for the efficient and controlled assembly of complex peptides and proteins in research and pharmaceutical development. It is essential for scientists and manufacturers in the fields of medicinal chemistry, bioconjugation, and proteomics who require reliable, high-quality reagents for advanced peptide production.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key reagent for the stepwise construction of peptides using Fmoc-chemistry protocols.
• Pharmaceutical Intermediate: Used in the research and development of novel therapeutic peptides and peptidomimetics.
• Bioconjugation: Serves as a linker or modified amino acid for attaching peptides to other molecules, surfaces, or biomolecules.
• Proteomics Research: Employed in the synthesis of custom peptide standards, antigens, and probes for biochemical assays.
• Combinatorial Chemistry: A valuable building block for generating diverse peptide libraries for drug discovery screening.
• Academic & Industrial R&D: Fundamental reagent for laboratories focused on synthetic chemistry and peptide science.

Basic Information

Product Name	Fmoc-Asp(Otbu)-Osu
CAS No.	78553-23-8
Molecular Formula	C27H30N2O8
Molecular Weight	510.54 g/mol
Synonyms	Fmoc-L-aspartic acid 4-tert-butyl ester N-succinimidyl ester; Fmoc-Asp(OtBu)-OSu; N-(9-Fluorenylmethoxycarbonyl)-L-aspartic acid β-tert-butyl ester N-succinimidyl ester; Fmoc-L-Asp(OtBu)-OSu; Fmoc-Asp(OtBu)-ONSu; N-α-Fmoc-L-aspartic acid 4-tert-butyl ester N-oxysuccinimide ester; Fmoc-Aspartate(OtBu)-Osu; N-Fmoc-L-aspartic acid β-tert-butyl ester N-hydroxysuccinimide ester
EINECS	Contact for details

Quality Control

Our Fmoc-Asp(Otbu)-Osu is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to industry best practices to support your research and cGMP-compliant development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below. This material is hygroscopic (moisture-sensitive); allow the sealed container to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤0.5%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.