Description

4-Keto-5-Amino-6-Hydroxyhexanoic Acid is a versatile chiral building block and intermediate in organic synthesis. This compound matters for its role in the production of complex molecules, particularly in the pharmaceutical sector where precise stereochemistry is critical. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of statin drugs and other therapeutic agents.
• Biochemical Research: Used as a precursor in enzymatic studies and metabolic pathway research.
• Agrochemical Synthesis: Intermediate in the production of advanced, targeted pesticides and herbicides.
• Fine Chemical Production: Building block for specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Peptide Mimetics: Utilized in the development of peptide analogs and conformationally restricted biomolecules.

Basic Information

Product Name	4-Keto-5-Amino-6-Hydroxyhexanoic Acid
CAS No.	78524-74-0
Molecular Formula	C6H11NO5
Molecular Weight	177.16 g/mol
Synonyms	5-Amino-4-oxo-6-hydroxyhexanoic acid; 6-Hydroxy-4-oxo-5-aminocaproic acid; (5S)-5-Amino-4-oxo-6-hydroxyhexanoic acid (stereoisomer); 4-Oxo-5-amino-6-hydroxycaproic acid; KAHHA; Statin side chain intermediate; L-4-Keto-5-amino-6-hydroxyhexanoic acid
EINECS	Contact for details

Quality Control

Our 4-Keto-5-Amino-6-Hydroxyhexanoic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.