Description

2-Propenal, 3-(4-Fluorophenyl)-2-Methyl- CAS NO 78495-95-1 is a specialized fluorinated α,β-unsaturated aldehyde, a key building block in advanced organic synthesis. This compound is valued for its unique molecular structure, which combines a reactive propenal moiety with a fluorinated aromatic ring, enabling precise chemical modifications. It is primarily utilized by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used to construct novel herbicides and fungicides, where the fluorine atom enhances biological activity and environmental stability.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with tailored optical or surface properties.
• Ligand and Catalyst Development: Employed in the creation of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized to develop fluorescent or affinity tags for studying biological processes.
• Academic & Industrial R&D: A versatile reagent for method development and exploring new reaction pathways in fluoroorganic chemistry.

Basic Information

Product Name	2-Propenal, 3-(4-Fluorophenyl)-2-Methyl-
CAS No.	78495-95-1
Molecular Formula	C10H9FO
Molecular Weight	164.18 g/mol
Synonyms	3-(4-Fluorophenyl)-2-methylpropenal; 2-Methyl-3-(4-fluorophenyl)acrylaldehyde; 4-Fluoro-α-methylcinnamaldehyde; (E)-3-(4-Fluorophenyl)-2-methylacrylaldehyde; (E)-2-Methyl-3-(4-fluorophenyl)propenal; p-Fluoro-α-methylcinnamaldehyde; 3-(p-Fluorophenyl)-2-methylacrolein; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of 2-Propenal, 3-(4-Fluorophenyl)-2-Methyl- is manufactured and tested under strict quality management systems to ensure batch-to-batch consistency and high purity for research and scale-up applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with stringent industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area. Recommended long-term storage temperature is 2-8°C. Allow the container to reach ambient temperature before opening to minimize moisture ingress and degradation. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Isomer Ratio (E/Z) (GC/HPLC)	Reported on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.