Description

Argipressin, Alanh2(9)- CAS NO 78338-40-6 is a synthetic nonapeptide analog of the endogenous hormone vasopressin, characterized by specific amino acid substitutions. This compound is of significant commercial and research interest due to its potent and selective pharmacological activity, primarily as a vasoconstrictor and antidiuretic agent. It is essential for pharmaceutical manufacturers, research institutions, and diagnostic developers engaged in cardiovascular research, hormone therapy, and the development of diagnostic reagents.

Application

• Pharmaceutical Active Ingredient (API): Core component in formulations for the treatment of conditions like diabetes insipidus and certain types of bleeding disorders (e.g., esophageal varices).
• Biomedical Research: Critical tool for studying vasopressin receptor (V1a, V2) signaling pathways, renal physiology, and cardiovascular function in preclinical models.
• Diagnostic Reagent: Used in in vitro diagnostic kits and assays to measure endocrine function or as a reference standard.
• Chemical Synthesis Intermediate: Serves as a key building block for the synthesis of more complex peptide derivatives or labeled analogs for tracer studies.
• Reference Standard: Provides a high-purity benchmark for quality control (QC) and analytical method development in pharmaceutical laboratories.

Basic Information

Product Name	Argipressin, Alanh2(9)- CAS NO 78338-40-6
CAS No.	78338-40-6
Molecular Formula	C₄₆H₆₅N₁₅O₁₂S₂
Molecular Weight	1084.2 g/mol
Synonyms	[Arg⁸]-Vasopressin; 8-Arginine Vasopressin; AVP; Argipressin; Vasopressin, 8-L-arginine-; Alanh2(9)-Argipressin; Antidiuretic Hormone (ADH) analog; 1-(3-Mercaptopropanoic acid)-2-(O-methyl-L-tyrosine)-8-L-arginine-vasopressin
EINECS	Contact for details

Quality Control

Our Argipressin is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including identification by HPLC and MS, purity assay, and tests for related substances and residual solvents, to ensure it meets stringent specifications for pharmaceutical and research use. Certificates of Analysis (COA) detailing all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at a controlled room temperature of 15-25°C or as specified on the label. Due to its hygroscopic (moisture-sensitive) nature, the product should be stored in a dry environment. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to theoretical mass
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0% (on anhydrous basis)
Bacterial Endotoxins	< 10.0 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.