Description

L-Aspartic Acid, [2,3-3H] is a high-specific-activity, tritium-labeled derivative of the essential amino acid L-aspartic acid. This radiolabeled compound is critical for advanced research requiring precise metabolic and biochemical pathway tracing. It is primarily utilized by research scientists and pharmaceutical developers in life sciences, particularly for studies in neuroscience, protein synthesis, and cellular metabolism. The product is supplied with guaranteed radiochemical purity and stability for reliable experimental results.

Application

• Biochemical Research: Used as a tracer in metabolic studies to investigate the Krebs cycle, amino acid metabolism, and neurotransmitter synthesis pathways.
• Pharmaceutical Development: Essential for ADME (Absorption, Distribution, Metabolism, and Excretion) studies of new drug candidates, especially those targeting neurological or metabolic disorders.
• Neuroscience Research: Applied in receptor binding assays and studies of excitatory neurotransmission, as aspartate is a known neurotransmitter.
• Protein & Peptide Labeling: Serves as a building block for incorporating tritium labels into peptides and proteins for turnover and localization studies.
• Enzymology: Used in assays to study the kinetics and mechanisms of enzymes like aspartate aminotransferase and enzymes involved in urea synthesis.
• Agricultural Chemistry: Employed in research on plant nitrogen metabolism and amino acid biosynthesis.

Basic Information

Product Name	L-Aspartic Acid, [2,3-3H]
CAS No.	78333-13-8
Molecular Formula	C4H53H2NO4 *
Molecular Weight	~135.1 g/mol (for unlabeled form)
Synonyms	(2S)-2-Aminobutanedioic-2,3-3H2 acid; L-Aspartic-2,3-3H2 acid; Tritiated L-Aspartic Acid; [2,3-3H]-L-Aspartate; H-3 Aspartic Acid; L-2-Aminosuccinic-2,3-3H2 acid; (S)-Aminobutanedioic-2,3-3H2 acid
EINECS	Contact for details

* Formula indicates tritium (3H) labeling at the 2 and 3 positions.

Quality Control

Every batch of L-Aspartic Acid, [2,3-3H] is manufactured and analyzed under strict quality systems. Our products undergo rigorous quality testing to ensure compliance with industry standards for radiolabeled compounds. Key parameters include radiochemical purity (typically >97% by HPLC), specific activity, and chemical purity. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be kept dry. For long-term storage, solutions are recommended to be prepared in appropriate buffers and stored frozen. Always follow local radiation safety regulations for handling and storage.

Specification

Item	Specification
Appearance	White to off-white solid or solution (as specified)
Identification (IR / NMR)	Conforms to structure
Assay (HPLC)	≥ 97% radiochemical purity
Specific Activity	10-60 Ci/mmol (Contact for exact value)
Chemical Purity (HPLC)	≥ 98%
Solvent (if supplied as solution)	Ethanol/Water or specified aqueous buffer
Radioactive Concentration	1 mCi/mL (typical, custom available)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.