Description

5-[[4-Methoxy-3-(Phenylmethoxy)Phenyl]Methyl]-2,4-Pyrimidinediamine is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the research and development of novel therapeutic agents, particularly in the field of kinase inhibition. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of targeted drug candidates. The material's specific molecular architecture makes it a valuable building block for creating potent and selective bioactive molecules.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel kinase inhibitor drugs for oncology and inflammatory diseases.
• Biochemical Research: Used as a reference standard or probe compound in enzymatic assays and target validation studies.
• Organic Synthesis: Serves as a versatile building block for constructing complex pyrimidine-based heterocycles in medicinal chemistry.
• Drug Discovery Programs: Employed in high-throughput screening and structure-activity relationship (SAR) optimization campaigns.
• Academic Research: Utilized in universities and research institutes for studying enzyme mechanisms and signal transduction pathways.
• Custom Synthesis: A starting material for the contract manufacturing of specialized APIs (Active Pharmaceutical Ingredients) under cGMP conditions.

Basic Information

Product Name	5-[[4-Methoxy-3-(Phenylmethoxy)Phenyl]Methyl]-2,4-Pyrimidinediamine
CAS No.	78233-99-5
Molecular Formula	C19H20N4O2
Molecular Weight	336.39 g/mol
Synonyms	5-[(4-Methoxy-3-benzyloxyphenyl)methyl]pyrimidine-2,4-diamine; 2,4-Pyrimidinediamine, 5-[[4-methoxy-3-(phenylmethoxy)phenyl]methyl]-; 5-((4-Methoxy-3-(benzyloxy)phenyl)methyl)pyrimidine-2,4-diamine; UNII-9J3U8V85E8; 9J3U8V85E8; BDBM50111657; CHEMBL3183082; DTXSID60422316
EINECS	Contact for details

Quality Control

Our 5-[[4-Methoxy-3-(Phenylmethoxy)Phenyl]Methyl]-2,4-Pyrimidinediamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent control of residual solvents and impurities. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with the rigorous standards required for pharmaceutical R&D and cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to prevent oxidation and moisture uptake. Keep the container tightly sealed in a desiccated environment when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.