Description

Procholecystokinin CAS NO 78206-77-6 is a synthetic peptide analog of the gastrointestinal hormone cholecystokinin (CCK). This compound is a critical research tool for studying digestive physiology, pancreatic secretion, and satiety signaling pathways. It is primarily utilized by pharmaceutical R&D departments, academic research institutions, and biotechnology companies engaged in metabolic and gastrointestinal disorder research.

Application

• Pharmacological Research: Used as a reference standard and active agent in studies investigating the role of CCK receptors in digestion, appetite regulation, and pain perception.
• Biochemical Assay Development: Serves as a key component in the development and validation of receptor binding assays, enzyme-linked immunosorbent assays (ELISAs), and other in vitro diagnostic tests.
• Neuroscience Studies: Employed in research exploring the gut-brain axis, particularly the effects of CCK on central nervous system functions related to anxiety and memory.
• Drug Discovery & Screening: Acts as a positive control or ligand in high-throughput screening (HTS) campaigns to identify novel agonists or antagonists for CCK receptor targets.
• Academic & Clinical Research: Essential for fundamental research into pancreatic exocrine function, gallbladder contraction, and intestinal motility.

Basic Information

Product Name	Procholecystokinin
CAS No.	78206-77-6
Molecular Formula	C₄₃H₅₈N₁₀O₉S₂
Molecular Weight	923.1 g/mol
Synonyms	CCK-8 (non-sulfated); H-Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2; Cholecystokinin Octapeptide (CCK-8); Sincalide; CCK-8 (sulfated form); Pro-CCK; CCK (26-33), non-sulfated; SQ 19,844
EINECS	Contact for details

Quality Control

Our Procholecystokinin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing all specifications and test results are provided to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by amino acid analysis)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.