Description

L-Glu-Gly-Gly-Gly-L-Asn-L-Arg-Gly-L-Asp-L-Pro-L-Ser-Gly-L-Val-S-[(2E,6E)-3,7,11-Trimethyl-2,6,10-Dodecatrien-1-Yl]-L-Cys-Oh is a specialized, high-purity synthetic peptide derivative designed for advanced research and development applications. This compound is valued for its unique structural features, including a farnesyl thioether modification, which is critical for studying protein prenylation, signal transduction, and biomolecular interactions. It is an essential building block for pharmaceutical researchers, biochemists, and life science companies focused on oncology, metabolic disorders, and novel therapeutic discovery. The precise synthesis and stringent quality control ensure reliability for sensitive in-vitro and pre-clinical studies.

Application

• Biochemical Research: Used as a key substrate or inhibitor in enzymatic studies related to protein prenylation and post-translational modifications.
• Pharmaceutical R&D: Serves as a critical intermediate or reference standard in the discovery and development of novel therapeutics targeting Ras-related signaling pathways.
• Proteomics & Cell Signaling: Employed to investigate the role of farnesylated peptides in intracellular trafficking, membrane association, and signal transduction mechanisms.
• Academic Research: Utilized in university and institutional labs for fundamental studies in biochemistry, molecular biology, and chemical biology.
• Diagnostic Development: Potential use in the development of assays and diagnostic tools for diseases associated with aberrant prenylation.
• Peptide Library Synthesis: Acts as a specialized component in the construction of peptide libraries for high-throughput screening and drug discovery platforms.

Basic Information

Item	Detail
Product Name	L-Glu-Gly-Gly-Gly-L-Asn-L-Arg-Gly-L-Asp-L-Pro-L-Ser-Gly-L-Val-S-[(2E,6E)-3,7,11-Trimethyl-2,6,10-Dodecatrien-1-Yl]-L-Cys-Oh
CAS No.	78150-10-4
Molecular Formula	C58H94N16O19S
Molecular Weight	1335.5 g/mol (approx.)
Synonyms	Farnesylated Peptide (EGGGNRGDPVSV-farnesyl-Cys-OH); S-Farnesylcysteine-containing Peptide; Prenylated Peptide Derivative; CAS 78150-10-4; L-Glutamyl-glycyl-glycyl-glycyl-L-asparaginyl-L-arginyl-glycyl-L-aspartyl-L-prolyl-L-seryl-glycyl-L-valyl-S-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]-L-cysteine; Farnesyl Thioether Peptide; Research Peptide 78150-10-4
EINECS	Contact for details

Quality Control

Our L-Glu-Gly-Gly-Gly-L-Asn-L-Arg-Gly-L-Asp-L-Pro-L-Ser-Gly-L-Val-S-[(2E,6E)-3,7,11-Trimethyl-2,6,10-Dodecatrien-1-Yl]-L-Cys-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and chiral analysis to ensure structural integrity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided to guarantee compliance with your research specifications. We support cGMP standards for advanced research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation or storage under inert atmosphere. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Assay (HPLC)	≥ 90% (on anhydrous basis)
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 70%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.