Description

Pyrimido[5,4-E]-1,2,4-Triazine-5,7(1H,6H)-Dione, 1,4-Diacetyl-2,3,4,8-Tetrahydro-6-Methyl- is a high-purity, heterocyclic organic compound with the CAS number 78105-49-4. This specialized chemical serves as a critical advanced intermediate for synthesizing complex molecules in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working on novel active ingredients. Its unique fused-ring structure makes it a valuable building block for developing compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in oncology and antiviral research.
• Agrochemical Research: Building block for developing new herbicides, fungicides, or insecticides with specific modes of action.
• Chemical Biology Probe: Used in academic and industrial research to study enzyme inhibition or protein-ligand interactions.
• Material Science Research: Potential monomer or precursor for creating specialty polymers with unique thermal or electronic properties.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services.

Basic Information

Product Name	Pyrimido[5,4-E]-1,2,4-Triazine-5,7(1H,6H)-Dione, 1,4-Diacetyl-2,3,4,8-Tetrahydro-6-Methyl-
CAS No.	78105-49-4
Molecular Formula	C11H12N4O4
Molecular Weight	264.24 g/mol
Synonyms	1,4-Diacetyl-2,3,4,8-tetrahydro-6-methylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione; 6-Methyl-1,4-diacetyl-1,2,3,4,6,8-hexahydropyrimido[5,4-e][1,2,4]triazine-5,7-dione; 1,4-Diacetyl-6-methyl-1,2,3,4,6,8-hexahydropyrimido[5,4-e][1,2,4]triazine-5,7-dione; Pyrimidotriazinedione derivative; CAS 78105-49-4
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing results from HPLC, NMR, and mass spectrometry. We support cGMP-compliant manufacturing for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.