Description

Argipressin, Asp(5)- is a synthetic analogue of the endogenous neurohypophyseal hormone vasopressin, specifically modified at the fifth amino acid position. This structural modification is critical for research into receptor specificity and the development of therapeutic agents targeting vasopressin pathways. It is an essential high-purity reference standard and intermediate for pharmaceutical R&D, particularly in endocrinology and cardiovascular research. The compound, identified by CAS No. 78031-79-5, is supplied to meet the stringent demands of advanced biochemical and pharmacological studies.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material for quality control and method validation in drug development and manufacturing.
• Biochemical Research: Serves as a key tool for studying vasopressin receptor (V1a, V1b, V2) binding affinity, signal transduction, and physiological effects.
• Peptide Chemistry Intermediate: Acts as a building block for the synthesis of more complex vasopressin analogues and peptide conjugates.
• Endocrinology Studies: Utilized in in vitro and in vivo research to investigate the role of vasopressin in water balance, blood pressure regulation, and stress response.
• Diagnostic Development: Employed in the development and calibration of immunoassays and other diagnostic tests for hormonal disorders.

Basic Information

Item	Detail
Product Name	Argipressin, Asp(5)-
CAS No.	78031-79-5
Molecular Formula	C₄₆H₆₅N₁₅O₁₂S₂
Molecular Weight	1084.2 g/mol
Synonyms	[8-Arginine]vasopressin, Aspartic acid-5-vasopressin, AVP(5-Asp), dAVP, Desmopressin analogue, 1-(3-Mercaptopropanoic acid)-2-(O-methyl-L-tyrosine)-8-L-arginine-vasopressin, [Asp5]Argipressin
EINECS	Contact for details

Quality Control

Our Argipressin, Asp(5)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing all critical quality attributes to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.