Description

Somatostatin 28, Trp(22)- CAS NO 77910-00-0 is a synthetic peptide analog of the endogenous hormone somatostatin, specifically modified at position 22 with tryptophan. This modification can influence its receptor binding affinity and metabolic stability, making it a valuable tool for advanced biochemical and pharmacological research. It is primarily utilized by research institutions and pharmaceutical developers focusing on endocrinology, neurobiology, and the development of novel therapeutic agents.

Application

• Biochemical Research: Used as a reference standard or active agent in studies investigating somatostatin receptor (SSTR) signaling pathways and hormone regulation.
• Pharmacological Development: Serves as a key intermediate or lead compound in the research and development of peptide-based therapeutics targeting hormonal disorders.
• In Vitro Diagnostics: Employed in the development and calibration of immunoassays (e.g., ELISA, RIA) for the detection and quantification of somatostatin-related activity.
• Academic Studies: Utilized in university and institutional labs for teaching and fundamental research in peptide chemistry and endocrinology.
• Drug Discovery Screening: Acts as a ligand in high-throughput screening (HTS) assays to identify and characterize new modulators of somatostatin receptors.

Basic Information

Product Name	Somatostatin 28, Trp(22)-
CAS No.	77910-00-0
Molecular Formula	C149H220N42O43S3
Molecular Weight	~3279.8 g/mol
Synonyms	Trp(22)-Somatostatin-28; Somatostatin-28 (22-Tryptophan); H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH (Disulfide bridge: Cys3-Cys14) with Trp at position 22; SRIF-28 (Trp22); Growth hormone release-inhibiting factor 28 (22-Trp); [Trp22]-Somatostatin-28
EINECS	Contact for details

Quality Control

Our Somatostatin 28, Trp(22)- is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing purity, peptide content, and impurity profiles are available upon request to ensure it meets your specific research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.