Description

Hemoglobin F Yamaguchi is a specialized biochemical reagent, a purified form of fetal hemoglobin (HbF) from the Yamaguchi variant. This high-purity compound is essential for research and diagnostic applications requiring a specific, well-characterized reference standard. It is primarily utilized by researchers and manufacturers in the fields of clinical diagnostics, hematology research, and biotechnology.

Application

• Reference Standard for Clinical Assays: Used as a calibrator or control material in diagnostic tests for hemoglobinopathies, such as sickle cell disease and thalassemia.
• Biochemical Research: Serves as a critical reagent in studies investigating the structure, function, and oxygen-binding properties of fetal hemoglobin.
• Pharmaceutical Development: Employed in research focused on therapies aimed at modulating HbF expression, a therapeutic target for sickle cell disease.
• Quality Control in Diagnostics: Acts as a material for verifying the accuracy and precision of HPLC, electrophoresis, and immunoassay systems in clinical laboratories.
• Educational & Training Material: Used in academic and professional training settings for teaching advanced concepts in hemoglobin biochemistry.

Basic Information

Product Name	Hemoglobin F Yamaguchi
CAS No.	77907-58-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	HbF Yamaguchi; Fetal Hemoglobin Yamaguchi; Hemoglobin F (Yamaguchi); γ-Globin Variant; HbF Variant; Human Fetal Hemoglobin Yamaguchi; Gly->Asp substitution at γ-75
EINECS	Contact for details

Quality Control

Our Hemoglobin F Yamaguchi is produced under stringent quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the exacting standards required for research and diagnostic use. Certificates of Analysis (COA) detailing purity (by HPLC), identity confirmation, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under appropriate conditions to prevent degradation.

Specification

Item	Specification
Appearance	Lyophilized powder
Identification (HPLC/Electrophoresis)	Conforms to HbF Yamaguchi standard
Purity (HPLC)	≥ 95%
Solubility	Soluble in water or specified buffer
Protein Content	Determined by UV absorbance
Endotoxin	< 1.0 EU/mg (where applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.