Description

ω-n-Hydroxymethylarginine is a chemically modified derivative of the amino acid L-arginine, featuring a hydroxymethyl group. This structural modification is of significant interest for advanced biochemical research and pharmaceutical development, particularly in the study of enzyme inhibition and protein modification pathways. It serves as a valuable synthetic intermediate and research chemical for scientists in the life sciences, pharmaceutical R&D, and specialty chemical synthesis sectors.

Application

• Pharmaceutical Research & Development: Utilized as a key synthetic intermediate or reference standard in the development of novel enzyme inhibitors and therapeutic agents.
• Biochemical Studies: Employed in research focused on nitric oxide synthase (NOS) pathways, arginine metabolism, and post-translational protein modifications.
• Peptide Synthesis: Acts as a specialized, modified amino acid building block for the synthesis of custom peptides with unique biological properties.
• Academic Research: Serves as a crucial reagent in university and institutional laboratories for investigating cellular signaling and metabolic processes.
• Diagnostic Reagent Development: Potential use in formulating reagents for clinical diagnostics related to arginine metabolic disorders.
• Enzyme Mechanism Probes: Used to study enzyme active sites and mechanisms due to its modified functional group.

Basic Information

Product Name	ω-n-Hydroxymethylarginine
CAS No.	77813-92-4
Molecular Formula	C7H16N4O3
Molecular Weight	204.23 g/mol
Synonyms	Nω-Hydroxymethyl-L-arginine; ω-N-Hydroxymethylarginine; L-arginine, N5-(hydroxymethyl)-; N5-(Hydroxymethyl)-L-arginine; Hydroxymethylarginine; HMA; (2S)-2-Amino-5-[(amino)(hydroxymethyl)amino]pentanoic acid
EINECS	Contact for details

Quality Control

Our ω-n-Hydroxymethylarginine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. A Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.