Description

α-Neoendorphin is a potent endogenous opioid peptide derived from the precursor protein proenkephalin B. This compound is of significant interest for its role in modulating pain perception and stress responses within the central nervous system. It is primarily utilized by researchers and developers in the fields of neuroscience, pharmacology, and drug discovery for studying opioid receptor pathways and developing novel therapeutic agents.

Application

• Neuroscience Research: Used as a reference standard and tool compound for studying the endogenous opioid system, receptor binding, and signal transduction.
• Pharmacological Studies: Employed in in vitro and in vivo assays to investigate analgesic mechanisms, tolerance, and dependence related to opioid peptides.
• Biochemical Analysis: Serves as a critical substrate or ligand in enzymatic studies, radioimmunoassays (RIA), and receptor autoradiography.
• Drug Discovery & Development: Acts as a lead compound or molecular template for the design and synthesis of novel analgesics with potentially improved efficacy and reduced side-effect profiles.
• Academic & Institutional Research: Essential for university and government lab studies focused on neuropeptides, neurobiology, and behavioral pharmacology.

Basic Information

Product Name	α-Neoendorphin
CAS No.	77739-20-9
Molecular Formula	C56H83N15O13
Molecular Weight	1150.36 g/mol
Synonyms	α-Neoendorphin; Dynorphin A (1-10); Dynorphin A 1-10; Leumorphin (1-10); Dynorphin-10; Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys; YGGFLRRIRPK; Dynorphin A Fragment 1-10
EINECS	Contact for details

Quality Control

Our α-Neoendorphin is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and MS for identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Solubility	Soluble in water, acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.