Description

L-Tyr-4-Methylsulfinyl-D-Abu-Gly-n-[(S)-1-Hydroxymethyl-2-Phenylethyl]-Nh2 is a specialized, non-natural peptide derivative designed for advanced research and development. This compound is valued for its unique structural features, including a methylsulfinyl group and a chiral phenylethyl moiety, which make it a critical intermediate in the synthesis of novel bioactive molecules. It is primarily sought by pharmaceutical and biotechnology R&D teams focused on peptide-based drug discovery, medicinal chemistry, and the development of enzyme inhibitors or receptor modulators.

Application

• Pharmaceutical Research Intermediate: Serves as a key building block in the synthesis of novel peptide-based drug candidates and pharmacologically active compounds.
• Medicinal Chemistry & SAR Studies: Used to explore structure-activity relationships (SAR) by introducing specific chiral and sulfoxide functionalities into peptide backbones.
• Enzyme Inhibitor Development: Acts as a precursor or core structure in the design of potential protease or kinase inhibitors due to its modified amino acid sequence.
• Bioconjugation & Probe Synthesis: Utilized in creating labeled peptides or affinity probes for biochemical and cellular assay development.
• Academic & Institutional Research: Supports fundamental studies in organic synthesis, peptide chemistry, and molecular biology within university and government laboratories.
• Custom Peptide Synthesis: Provided as a raw material for contract research organizations (CROs) and CDMOs specializing in custom peptide manufacturing.

Basic Information

Product Name	L-Tyr-4-Methylsulfinyl-D-Abu-Gly-n-[(S)-1-Hydroxymethyl-2-Phenylethyl]-Nh2
CAS No.	77702-18-2
Molecular Formula	C26H35N3O6S
Molecular Weight	517.64 g/mol
Synonyms	L-Tyrosine, 4-[(methylsulfinyl)methyl]-D-2-aminobutanoic acid glycyl-N-[(1S)-1-(hydroxymethyl)-2-phenylethyl]amide; (S)-2-Amino-N-((S)-1-(hydroxymethyl)-2-phenylethyl)-3-(4-((methylsulfinyl)methyl)phenyl)propanamide; Peptide derivative 77702-18-2; 4-Methylsulfinyl-D-Abu-Gly-Phenylethanolamine conjugate; Tyr(MeSO)-D-Abu-Gly-HMPhEt-NH2; Custom peptide intermediate 77702-18-2
EINECS	Contact for details

Quality Control

Our L-Tyr-4-Methylsulfinyl-D-Abu-Gly-n-[(S)-1-Hydroxymethyl-2-Phenylethyl]-Nh2 is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and chiral analysis to ensure stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific research or cGMP guidelines for non-clinical use upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment. For long-term storage, consider desiccant and inert atmosphere conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area%)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.