Description

Oxytocin, 1-Desamino-(o-Et-Tyr)(2)- is a synthetic analogue of the neurohypophysial hormone oxytocin, specifically modified at the first and second amino acid positions to enhance its stability and receptor-binding profile. This modification is critical for research and development applications requiring a compound with a longer biological half-life and altered pharmacological activity compared to the native peptide. It is primarily utilized by pharmaceutical researchers, peptide chemists, and biotech companies engaged in advanced neuroendocrine studies, drug discovery, and the development of novel therapeutic agents targeting the oxytocin receptor pathway.

Application

• Pharmacological Research: Used as a key reference standard and tool compound in studies investigating the structure-activity relationship (SAR) of oxytocin receptor agonists and antagonists.
• Drug Discovery Programs: Serves as a lead compound or intermediate in the development of new therapeutics for conditions related to social behavior, stress, and reproduction.
• Biochemical Assay Development: Employed in the calibration and validation of receptor-binding assays (e.g., radioligand binding assays) and functional cellular assays for oxytocin receptor activity.
• Peptide Chemistry & Synthesis: Acts as a model compound for developing and optimizing synthetic routes for complex, modified peptides.
• Neuroscience Studies: Applied in preclinical research to explore the role of oxytocin pathways in neural circuits, behavior, and neuropsychiatric disorders.
• Stability & Formulation Studies: Utilized to study the degradation pathways and stabilization strategies for peptide-based pharmaceuticals.

Basic Information

Product Name	Oxytocin, 1-Desamino-(o-Et-Tyr)(2)-
CAS No.	77648-79-4
Molecular Formula	C₄₅H₆₆N₁₂O₁₂S₂
Molecular Weight	1007.2 g/mol
Synonyms	1-Desamino-2-O-ethyltyrosine-oxytocin; [O-Et-Tyr²]-1-desamino-oxytocin; 1-β-Mercaptopropionic acid-2-O-ethyltyrosine-oxytocin; Desamino-O-Et-Tyr²-oxytocin; Oxytocin, 1-desamino-2-O-ethyltyrosine-; (o-Et-Tyr²)-1-desamino-oxytocin; HOE 893 d; A synthetic oxytocin analogue
EINECS	Contact for details

Quality Control

Our Oxytocin, 1-Desamino-(o-Et-Tyr)(2)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Single Impurity (HPLC)	≤ 2.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.