Description

n-Formylmethionyl Sulfoxide-Leucyl-Phenylalanine CAS NO 77543-03-4 is a synthetic peptide derivative of significant interest in biochemical and pharmaceutical research. This compound serves as a key intermediate and a model substrate for studying enzymatic processes, particularly those involving formylmethionine and peptide bond cleavage. It is primarily utilized by research institutions, pharmaceutical developers, and biotechnology companies engaged in proteomics, enzyme kinetics, and the development of novel therapeutic agents.

Application

• Biochemical Research: Used as a specialized substrate for studying the activity and specificity of proteolytic enzymes, including various proteases and peptidases.
• Pharmaceutical Development: Acts as a critical intermediate in the synthesis and screening of peptide-based drug candidates and enzyme inhibitors.
• Proteomics & Cell Signaling: Employed in research focused on N-formyl peptide receptors and their role in immune cell chemotaxis and inflammatory responses.
• Enzyme Kinetics: Serves as a model compound to investigate reaction mechanisms, kinetic parameters, and inhibition profiles of enzymes that process formylated peptides.
• Academic Research: Utilized in university and institutional labs for teaching and advanced studies in peptide chemistry and molecular biology.
• Reference Standard: Provides a high-purity standard for analytical method development, validation, and quality control in peptide analysis.

Basic Information

Product Name	n-Formylmethionyl Sulfoxide-Leucyl-Phenylalanine
CAS No.	77543-03-4
Molecular Formula	C26H40N4O7S
Molecular Weight	560.68 g/mol
Synonyms	N-Formyl-Met(O)-Leu-Phe; fMet(O)-Leu-Phe; N-Formylmethionine Sulfoxide-Leucine-Phenylalanine; For-Met(O)-Leu-Phe-OH; Formylmethionylsulfinylleucylphenylalanine; Chemotactic Peptide fMLF Sulfoxide; N-Formyl-L-methionyl-L-leucyl-L-phenylalanine S-oxide; Formyl-Met-Leu-Phe Sulfoxide
EINECS	Contact for details

Quality Control

Our n-Formylmethionyl Sulfoxide-Leucyl-Phenylalanine is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and chiral analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. For long-term storage, consider storing under inert atmosphere at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0% (on anhydrous basis)
Water Content (KF)	≤ 3.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.