Description

S-2-Histidylcysteine is a specialized dipeptide composed of the amino acids histidine and cysteine, linked via a peptide bond. This compound is of significant interest in biochemical research and pharmaceutical development due to its unique structure, which incorporates the reactive thiol group of cysteine and the imidazole ring of histidine. It is primarily utilized by researchers and manufacturers in the fields of peptide synthesis, enzyme mechanism studies, and as a potential precursor for bioactive molecules or chelating agents. The product is supplied with a CAS registry number of 77504-36-0.

Application

• Biochemical Research: Used as a standard or building block in studies of peptide structure, function, and metal-binding properties.
• Pharmaceutical Intermediates: Serves as a key synthetic precursor for developing novel therapeutic peptides or drug candidates.
• Enzymology Studies: Applied in research to investigate enzyme active sites, particularly those involving cysteine and histidine residues.
• Chelation Chemistry: Explored for its potential as a ligand in metal chelation due to the presence of thiol and imidazole functional groups.
• Nutritional Science: Investigated for its role in metabolic pathways and as a component in specialized nutritional formulations.
• Cosmetic Peptide Synthesis: Potential use as an ingredient in the synthesis of bioactive peptides for cosmetic applications.

Basic Information

Product Name	S-2-Histidylcysteine
CAS No.	77504-36-0
Molecular Formula	C9H14N4O3S
Molecular Weight	258.30 g/mol
Synonyms	L-Histidyl-L-cysteine; Histidine-cysteine dipeptide; H-Cys-His-OH; Cys-His; L-Cysteine, L-histidyl-; NSC 334904; 2-[(2-Amino-2-carboxyethyl)amino]-3-(1H-imidazol-4-yl)propanoic acid; S-Histidylcysteine
EINECS	Contact for details

Quality Control

Our S-2-Histidylcysteine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as assay, chiral purity, and impurity profiles. While specific pharmacopeial monographs may not be established for this research chemical, our quality systems are designed to meet the exacting standards required for pharmaceutical and life science research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider maintaining under an inert atmosphere (e.g., nitrogen or argon) to preserve stability and prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Chiral Purity (HPLC)	≥ 98.0% (L,L-isomer)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.