Description

Tolpadol CAS NO 77502-27-3 is a specialized pharmaceutical intermediate belonging to the class of synthetic organic compounds. This high-purity chemical is critical for ensuring the quality and consistency of downstream active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical industry engaged in the development and production of analgesic and central nervous system (CNS) active drugs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel analgesic and neuroactive pharmaceutical compounds.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new therapeutic agents.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.
• Preclinical Studies: Employed in the formulation of compounds for pharmacological and toxicological evaluation.
• Chemical Synthesis: Utilized in organic synthesis for constructing complex molecular architectures with specific pharmacological profiles.

Basic Information

Item	Details
Product Name	Tolpadol
CAS No.	77502-27-3
Molecular Formula	C17H23NO2
Molecular Weight	273.37 g/mol
Synonyms	1-Methyl-4-phenyl-4-piperidinol propionate; 4-Phenyl-1-methyl-4-piperidinyl propionate; Tolpadol; Propanoic acid, 4-phenyl-1-methyl-4-piperidinyl ester; 4-Phenyl-1-methylpiperidin-4-yl propionate
EINECS	Contact for details

Quality Control

Our Tolpadol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) detailing all test results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from moisture and direct light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.