Description

5-Bromo-2-(Isopropylamino)Pyrimidine is a high-purity brominated pyrimidine derivative, a crucial building block in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules with tailored biological and chemical properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), especially kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Chemical Synthesis Building Block: Serves as a versatile precursor for further functionalization via cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to create diverse pyrimidine libraries.
• Material Science Research: Employed in the development of organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic semiconductors.
• Biochemical Probe Development: Utilized in medicinal chemistry to create molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	5-Bromo-2-(Isopropylamino)Pyrimidine
CAS No.	77476-95-0
Molecular Formula	C7H10BrN3
Molecular Weight	216.08 g/mol
Synonyms	2-Amino-5-bromo-N-isopropylpyrimidine; 5-Bromo-2-(isopropylamino)pyrimidine; 2-(Isopropylamino)-5-bromopyrimidine; 5-Bromo-N-isopropylpyrimidin-2-amine; 5-Bromo-2-(propan-2-ylamino)pyrimidine; 77476-95-0; 5-Br-2-iPrNH-Pyrimidine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-(Isopropylamino)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring high-purity intermediates for GLP and cGMP environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.