Description

Pimobendan (Hydrochloride) is a selective phosphodiesterase III inhibitor with positive inotropic and vasodilatory effects. This compound is a critical active pharmaceutical ingredient (API) primarily used in veterinary cardiology for the management of congestive heart failure. It is essential for pharmaceutical manufacturers and research institutions developing treatments for cardiac conditions. The product is supplied as a high-purity material suitable for formulation and advanced research applications.

Application

• Veterinary Pharmaceutical API: Primary active ingredient in medications for canine congestive heart failure (CHF), such as inodilator therapy.
• Pharmaceutical R&D: Used in preclinical and clinical research for investigating cardiac pharmacology and new therapeutic formulations.
• Reference Standard: Serves as a high-purity analytical standard for quality control testing in pharmaceutical manufacturing.
• Chemical Intermediate: Utilized in the synthesis of more complex molecules or derivative compounds in medicinal chemistry programs.
• Academic Research: Employed in university and institutional studies focusing on cardiovascular physiology and PDE III inhibition mechanisms.

Basic Information

Product Name	Pimobendan (Hydrochloride)
CAS No.	77469-98-8
Molecular Formula	C19H19N5O2 • HCl
Molecular Weight	409.85 g/mol (Hydrochloride salt)
Synonyms	UD-CG 212; 4,5-Dihydro-6-[2-(4-methoxyphenyl)-1H-benzimidazol-5-yl]-5-methyl-3(2H)-pyridazinone Hydrochloride; Pimobendan HCl; (+)-Pimobendan Hydrochloride; (R)-Pimobendan Hydrochloride; Vetmedin (brand name reference); 6-(2-(4-Methoxyphenyl)-1H-benzimidazol-5-yl)-5-methyl-4,5-dihydro-3(2H)-pyridazinone Hydrochloride
EINECS	Contact for details

Quality Control

Our Pimobendan (Hydrochloride) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting high standards for pharmaceutical use. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, related substances, and residual solvents. We support compliance with cGMP and relevant pharmacopeial guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.