Description

β-Mercapto-Beta,β-Cyclopentamethylene-Propionyl-Tyr(Et)-Phe-Val-Asn-Cys-Pro-Arg-Gly-Nh2 is a synthetic, chemically modified peptide sequence of significant interest in advanced pharmaceutical research and development. This compound is valued for its specific structural features, including a cyclopentamethylene bridge and a β-mercapto group, which are engineered to enhance stability and biological activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery of novel therapeutic agents, particularly in areas requiring precise molecular targeting. The CAS number for this compound is 77453-01-1.

Application

• Pharmaceutical R&D as a key intermediate or active pharmaceutical ingredient (API) in novel drug discovery programs.
• Bioconjugation Studies leveraging the reactive thiol group for site-specific labeling or coupling with other biomolecules.
• Peptide-Based Therapeutic Development for targeting specific receptors or enzymes due to its engineered sequence and conformation.
• Biochemical Research as a tool compound to study protein-protein interactions, enzyme inhibition, or signal transduction pathways.
• Preclinical Investigation of metabolic stability, pharmacokinetics, and pharmacodynamics of modified peptide structures.
• Reference Standard for analytical method development and validation in quality control laboratories.

Basic Information

Product Name	β-Mercapto-Beta,β-Cyclopentamethylene-Propionyl-Tyr(Et)-Phe-Val-Asn-Cys-Pro-Arg-Gly-Nh2
CAS No.	77453-01-1
Molecular Formula	C58H86N14O13S2
Molecular Weight	1227.5 g/mol (approx.)
Synonyms	β-Mercapto-Beta,β-Cyclopentamethylene-Propionyl-Tyrosine(Ethyl)-Phenylalanine-Valine-Asparagine-Cysteine-Proline-Arginine-Glycinamide; Cyclopentamethylene-modified Peptide; 77453-01-1; H-Cys-Pro-Arg-Gly-NH2 modified peptide; Thiol-functionalized cyclic peptide derivative; Tyr(Et)-containing mercapto peptide; BMBCTP-Y(Et)-F-V-N-C-P-R-G-NH2; Research Peptide 77453-01-1
EINECS	Contact for details

Quality Control

Our β-Mercapto-Beta,β-Cyclopentamethylene-Propionyl-Tyr(Et)-Phe-Val-Asn-Cys-Pro-Arg-Gly-Nh2 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and MS for identity confirmation, to ensure it meets exacting research-grade specifications. Certificates of Analysis (COA) detailing purity, related substances, and other critical parameters are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic and moisture-sensitive nature, containers should be sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent oxidation and degradation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Total Impurities (HPLC)	≤ 5.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.