Description

N(G)-Methylagmatine is a methylated derivative of the endogenous polyamine agmatine, playing a significant role in cellular signaling and metabolic pathways. This compound is valued for its high purity and stability, making it a critical intermediate and reference standard in advanced biochemical research and development. It is primarily sought by professionals in the pharmaceutical, life sciences, and nutraceutical industries for applications in neuroscience, metabolic studies, and the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Research: Used as a key intermediate in the synthesis and development of novel therapeutic agents targeting neurological and metabolic disorders.
• Biochemical Reference Standard: Serves as a high-purity analytical standard for quantitative and qualitative analysis in HPLC, LC-MS, and other chromatographic methods.
• Neuroscience Studies: Employed in research to investigate its interactions with imidazoline and α-2 adrenergic receptors, elucidating its potential neuroprotective and neuromodulatory effects.
• Metabolic Pathway Analysis: A tool for studying polyamine metabolism and its downstream effects on nitric oxide synthase and mitochondrial function.
• Nutraceutical Development: Explored as a potential active ingredient in dietary supplements focused on cognitive support and metabolic health.
• Enzyme Inhibition Studies: Used to study its effects on enzymes like nitric oxide synthase (NOS) and diamine oxidase.

Basic Information

Product Name	N(G)-Methylagmatine
CAS No.	77414-15-4
Molecular Formula	C6H16N4
Molecular Weight	144.22 g/mol
Synonyms	Nω-Methylagmatine; 1-(4-Aminobutyl)-2-methylguanidine; 2-Methyl-1-(4-aminobutyl)guanidine; Agmatine, N-methyl-; N-Methylagmatine; N(G)-Methylagmatine sulfate (salt form); Methylagmatine
EINECS	Contact for details

Quality Control

Our N(G)-Methylagmatine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.