Description

N6-Octanoyl CAS NO 77378-05-3 is a specialized biochemical intermediate, specifically an octanoylated derivative of a nucleobase. This compound is of significant value in advanced research and development due to its role as a key building block in the synthesis of modified nucleotides and oligonucleotides. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for applications in drug discovery, molecular diagnostics, and nucleic acid chemistry.

Application

• Nucleic Acid Research: Serves as a crucial precursor in the synthesis of chemically modified nucleosides and nucleotides for structure-activity relationship (SAR) studies.
• Antisense Oligonucleotide (ASO) Development: Used in the creation of backbone-modified oligonucleotides to enhance stability, specificity, and cellular uptake for therapeutic applications.
• Probe and Primer Synthesis: Enables the incorporation of specific functional groups or labels into DNA/RNA probes and primers for advanced molecular diagnostics and sequencing.
• Pharmaceutical Intermediates: Acts as a key synthetic intermediate in the development of novel antiviral and anticancer nucleoside analog drugs.
• Bioconjugation Chemistry: Provides a reactive handle for linking nucleic acid components to other molecules, such as peptides, fluorophores, or delivery vehicles.
• Academic and Industrial R&D: Essential for fundamental research in biochemistry and molecular biology exploring nucleic acid function and modification.

Basic Information

Product Name	N6-Octanoyl CAS NO 77378-05-3
CAS No.	77378-05-3
Molecular Formula	C13H19N5O5
Molecular Weight	325.32 g/mol
Synonyms	N6-Octanoyl-2'-deoxyadenosine; 2'-Deoxy-N6-octanoyladenosine; N6-Octanoyl-deoxyadenosine; dAOct; Octanoyl-modified dA; 9-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-octanoylaminopurine
EINECS	Contact for details

Quality Control

Our N6-Octanoyl is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemical and biochemical intermediates, with specifications available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.