Description

Oxytocin, 1-(1-Mercaptocyclohexaneacetic Acid)-(Oet-Tyr)(2)-Orn(8)- CAS NO 77327-46-9 is a synthetic, modified peptide analog of the neurohypophysial hormone oxytocin, designed for enhanced stability and specific receptor interaction. This compound is critical for advanced research and development in neuroendocrinology and peptide-based therapeutics, offering a valuable tool for studying oxytocinergic pathways. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on central nervous system disorders, social behavior research, and next-generation peptide drug discovery.

Application

• Neuroscientific Research: A key reagent for in vitro and in vivo studies investigating the role of oxytocin in social bonding, stress response, and maternal behavior.
• Drug Discovery & Development: Serves as a lead compound or reference standard in the development of novel therapeutics for autism spectrum disorders, anxiety, depression, and schizophrenia.
• Biochemical Assay Development: Used as a high-purity ligand in receptor binding assays (e.g., oxytocin receptor binding studies) and functional cellular assays to screen for agonists or antagonists.
• Peptide Chemistry & Stability Studies: Employed as a model compound to study the effects of structural modifications (like the mercaptocyclohexaneacetic acid moiety) on peptide stability, bioavailability, and metabolic resistance.
• Veterinary Pharmaceutical Research: Investigated for applications in animal health, particularly in livestock management for parturition and lactation studies.
• Reference Standard: Provides an essential analytical standard for quality control and method validation in peptide synthesis and purification processes.

Basic Information

Item	Details
Product Name	Oxytocin, 1-(1-Mercaptocyclohexaneacetic Acid)-(Oet-Tyr)(2)-Orn(8)-
CAS No.	77327-46-9
Molecular Formula	C46H68N12O12S2
Molecular Weight	1021.22 g/mol
Synonyms	1-Mercaptocyclohexaneacetic Acid Oxytocin; [1-Mercaptocyclohexaneacetic acid, O-ethyl-L-tyrosine, ornithine8]-Oxytocin; Oxytocin (1-(1-Mercaptocyclohexaneacetic acid)-(Oet-Tyr)(2)-Orn(8)-); Modified Oxytocin Analog; Ornithine8-Oxytocin derivative; Tocinoic acid analog; CAS 77327-46-9
EINECS	Contact for details

Quality Control

Our Oxytocin analog is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. While produced for research use, our quality protocols align with the stringent principles of GMP for active pharmaceutical ingredients (APIs) where applicable. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment to maintain long-term stability, considering its hygroscopic and easily oxidized nature. For short-term use, the product may be stored at 2-8°C. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. Store under an inert atmosphere when handling bulk quantities.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum consistent with molecular weight
Purity (HPLC)	≥ 95.0%
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.