Description

Didemnin B is a potent cytotoxic depsipeptide compound originally isolated from marine tunicates. Its primary value lies in its significant biological activity, which has made it a crucial reference standard and a key compound for biomedical research and development. This product is essential for researchers and organizations in the pharmaceutical, biotechnology, and academic sectors focused on oncology, virology, and novel therapeutic discovery.

Application

• Biomedical Research Standard: Serves as a high-purity reference material for analytical method development and validation in laboratory studies.
• Anticancer Agent Research: Used as a lead compound or biological probe in studies investigating mechanisms of apoptosis, cell cycle inhibition, and tumor growth suppression.
• Antiviral Studies: Employed in virology research to explore its documented activity against certain DNA and RNA viruses.
• Pharmacology & Toxicology: Utilized in preclinical studies to understand the pharmacokinetics, metabolism, and safety profile of depsipeptide-class molecules.
• Chemical Biology: Acts as a tool compound for studying protein synthesis inhibition and its effects on cellular processes.
• Academic & Institutional Research: Supplied to universities and research institutes for fundamental studies in marine natural products and medicinal chemistry.

Basic Information

Product Name	Didemnin B
CAS No.	77327-05-0
Molecular Formula	C57H87N7O15
Molecular Weight	1110.34 g/mol
Synonyms	NSC 325319; Dehydrodidemnin B; Aplidine; (3S,6R,9S,12S,15S,18S,21S,24S,30S,33S)-30-[(2S)-butan-2-yl]-21-(2-methylpropyl)-3,6,9,12,15,18,24-heptamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaoxo-33-(propan-2-yl)-1λ⁵,4λ⁵,7λ⁵,10λ⁵,13λ⁵,16λ⁵,19λ⁵,22λ⁵,25λ⁵,28λ⁵,31λ⁵-undecathia-34-azatetracyclo[31.3.0.0²,²⁶.0¹¹,³⁵]hexatriacontane-34,36-dione
EINECS	Contact for details

Quality Control

Our Didemnin B is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for critical research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant research and development standards, and specifications can be provided to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, controlled environment. Due to its hygroscopic (moisture-sensitive) nature, containers should be allowed to equilibrate to room temperature before opening to prevent condensation. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.