Description

2''-Formimidoylistamycin B is a chemically modified derivative of the lincosamide antibiotic, lincomycin. This compound is of significant interest in pharmaceutical research and development, particularly for the synthesis of novel semi-synthetic antibiotics aimed at overcoming bacterial resistance. It serves as a crucial advanced intermediate for researchers and manufacturers in the pharmaceutical industry focused on developing next-generation antimicrobial agents.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel semi-synthetic lincosamide antibiotics.
• Antimicrobial Research: Used in R&D to study structure-activity relationships (SAR) and develop new compounds with improved efficacy against resistant bacteria.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Studies: Employed in microbiological and biochemical research to investigate mechanisms of antibiotic action and resistance.

Basic Information

Product Name	2''-Formimidoylistamycin B
CAS No.	77312-55-1
Molecular Formula	C19H33N3O6S
Molecular Weight	431.55 g/mol
Synonyms	2''-Formimidoyllincomycin B; (2S,4R)-N-[(1S,2S,3R,4R,6R)-4-[(2S,3R,4S,6R)-3,4-Dihydroxy-6-(methylthio)tetrahydro-2H-pyran-2-yl]oxy-2,3-dihydroxy-6-methylcyclohexyl]-1-(4-imidazolyl)-2-methyl-1-oxopropan-2-amine; Lincomycin B, 2''-formimidoyl-; Formimidoyllincomycin B; U-24729A; Antibiotic U-24729A
EINECS	Contact for details

Quality Control

Our 2''-Formimidoylistamycin B is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.