Description

β-Endorphin Ac Argo is a synthetic peptide fragment of the endogenous opioid peptide β-endorphin, featuring an acetylated N-terminus and an arginine-glycine (Arg-Gly) motif. This modification enhances its stability and receptor interaction profile, making it a valuable tool for advanced biochemical and pharmacological research. It is primarily utilized by research institutions, pharmaceutical R&D departments, and diagnostic manufacturers for studying pain pathways, neuroendocrine functions, and developing novel therapeutic agents.

Application

• Neuroscience Research: Used as a reference standard and active agent in studies of opioid receptor binding, signal transduction, and the central nervous system's role in pain modulation and stress response.
• Pharmacological Assay Development: Serves as a critical component in high-throughput screening (HTS) assays and in vitro models to identify and characterize new analgesic or neuroprotective compounds.
• Biochemical Standard: Employed as a calibrated standard in mass spectrometry (MS), high-performance liquid chromatography (HPLC), and immunoassay techniques for quantitative analysis of endorphin pathways.
• Diagnostic Reagent Manufacturing: Incorporated into the production of ELISA kits, radioimmunoassay (RIA) kits, and other diagnostic tools for measuring endorphin levels in clinical and research settings.
• Peptide Chemistry & Conjugation: Acts as a starting material or model compound for further chemical modifications, conjugation to carriers, or stability studies due to its acetylated structure.

Basic Information

Product Name	β-Endorphin Ac Argo
CAS No.	77303-81-2
Molecular Formula	C158H251N47O46S
Molecular Weight	3466.0 g/mol (approximately)
Synonyms	β-Endorphin (1-31), N-acetyl-Arg-Gly-; Ac-β-Endorphin (1-31); N-Acetyl-β-endorphin; Acetylated β-Endorphin; β-Lipotropin (61-91), N-acetyl-; H-Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Ala-Tyr-Lys-Lys-Gly-Glu-OH (N-acetylated); Opioid peptide fragment; Analgesic peptide
EINECS	Contact for details

Quality Control

Every batch of β-Endorphin Ac Argo is manufactured and analyzed under strict quality management protocols. We provide comprehensive analytical data to ensure identity, purity, and consistency for critical research applications. A Certificate of Analysis (COA) detailing results for purity (HPLC), peptide content, amino acid analysis, and mass spectrometry is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture absorption. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Molecular weight confirmed by mass spectrometry
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Analysis	± 10% of theoretical composition
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	Reported on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.