Description

H-D-Ala-Gly-Gly-Oh is a synthetic tripeptide derivative of significant interest in advanced biochemical research and pharmaceutical development. This compound serves as a crucial building block and a model substrate for studying enzyme specificity, peptide stability, and metabolic pathways. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in proteomics, peptidomimetic drug design, and the synthesis of more complex bioactive peptides. Its defined structure and high purity make it an essential tool for precise scientific investigation.

Application

• Pharmaceutical Research & Development: As a key intermediate in the synthesis of novel peptide-based therapeutics and diagnostic agents.
• Biochemical Substrate: Used as a specific substrate to study the activity and inhibition profiles of proteolytic enzymes like peptidases and proteases.
• Proteomics & Metabolic Studies: Employed in research to understand peptide degradation pathways, transport mechanisms, and stability under various physiological conditions.
• Peptidomimetics: Acts as a foundational scaffold for the design and development of peptidomimetic compounds with enhanced bioavailability and metabolic stability.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in peptide analysis using HPLC or LC-MS.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic chemistry, medicinal chemistry, and biochemistry.

Basic Information

Product Name	H-D-Ala-Gly-Gly-Oh
CAS No.	77286-90-9
Molecular Formula	C7H13N3O4
Molecular Weight	203.20 g/mol
Synonyms	D-Alanyl-glycyl-glycine; H-D-Ala-Gly-Gly-OH; (R)-2-((2-Aminoacetamido)acetamido)propanoic acid; D-Ala-Gly-Gly; Glycyl-glycyl-D-alanine; D-Alanine-Glycine-Glycine; DAG; D-Ala-GG; D-AGG
EINECS	Contact for details

Quality Control

Our H-D-Ala-Gly-Gly-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques. While produced to meet general reagent and research-grade standards, specifications can be aligned with specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. For long-term storage, consider desiccated environments.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	< 10 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.