Description

Ac-Tyr(So3H)-Met-Gly-Trp-Met-Asp-Phe-Nh2 is a chemically modified, sulfonated peptide sequence of significant interest in advanced biochemical research and development. This compound matters for its role as a specialized tool in studying enzyme-substrate interactions, receptor binding, and signal transduction pathways where tyrosine sulfation is a critical post-translational modification. It is primarily needed by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on peptide therapeutics, diagnostic assay development, and proteomics.

Application

• Biochemical Research: Used as a reference standard or substrate in enzymatic studies, particularly for kinases, phosphatases, and sulfotransferases.
• Pharmaceutical Development: Serves as a key intermediate or analog in the discovery and optimization of novel peptide-based drugs targeting GPCRs and other receptors.
• Diagnostic Reagents: Employed in the development of immunoassays and biosensors to detect specific antibodies or study protein-protein interactions.
• Proteomics & Signal Transduction: Acts as a tool peptide to investigate cell signaling cascades and the functional impact of tyrosine O-sulfation.
• Structure-Activity Relationship (SAR) Studies: Utilized to map binding epitopes and understand the contribution of sulfated tyrosine to biological activity and stability.

Basic Information

Item	Details
Product Name	Ac-Tyr(So3H)-Met-Gly-Trp-Met-Asp-Phe-Nh2
CAS No.	77275-51-5
Molecular Formula	C52H68N10O17S3
Molecular Weight	1201.34 g/mol
Synonyms	Acetyl-Tyrosine(Sulfonic Acid)-Methionyl-Glycyl-Tryptophyl-Methionyl-Aspartyl-Phenylalanine amide; N-Acetyl-O-sulfo-L-tyrosyl-L-methionylglycyl-L-tryptophyl-L-methionyl-L-α-aspartyl-L-phenylalaninamide; Sulfated Tyrosine Peptide; H-Ac-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2; Ac-Y(sO3)-M-G-W-M-D-F-NH2; Tyr(SO3H)-containing Heptapeptide; CCK-8 related peptide analog
EINECS	Contact for details

Quality Control

Our Ac-Tyr(So3H)-Met-Gly-Trp-Met-Asp-Phe-Nh2 is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic (moisture-sensitive) nature, allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.