Description

Pyrimidine, 2-[4-(Bromomethyl)Phenyl]-5-Methyl- (9Ci) is a specialized brominated pyrimidine derivative that serves as a crucial building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate, enabling the introduction of both a reactive bromomethyl handle and a pyrimidine core into target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of small molecule drugs, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a precursor for functionalized organic molecules used in organic light-emitting diodes (OLEDs) and liquid crystals.
• Chemical Biology: Employed in the synthesis of molecular probes and labeled compounds for biochemical assays.
• Cross-Coupling Reactions: The bromomethyl group facilitates further functionalization via Suzuki, Heck, or other palladium-catalyzed cross-coupling reactions.
• Academic & R&D: A valuable reagent for methodological development and exploring new reaction pathways in synthetic organic chemistry.

Basic Information

Product Name	Pyrimidine, 2-[4-(Bromomethyl)Phenyl]-5-Methyl- (9Ci)
CAS No.	77232-36-1
Molecular Formula	C12H11BrN2
Molecular Weight	263.14 g/mol
Synonyms	2-[4-(Bromomethyl)phenyl]-5-methylpyrimidine; 5-Methyl-2-[4-(bromomethyl)phenyl]pyrimidine; 4'-(Bromomethyl)-5-methyl-2-phenylpyrimidine; 2-(4-(Bromomethyl)phenyl)-5-methylpyrimidine; 77232-36-1; 4-(Bromomethyl)phenyl-5-methyl-2-pyrimidine; 5-Methyl-2-(4-bromomethylphenyl)pyrimidine
EINECS	Contact for details

Quality Control

Our Pyrimidine, 2-[4-(Bromomethyl)Phenyl]-5-Methyl- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.