Description

Somatostatin, Seleno-Cys(3,14)-Trp(8)- is a synthetic, selenium-containing analogue of the endogenous peptide hormone somatostatin, identified by CAS No. 77201-60-6. This modified peptide is of significant interest for advanced biochemical and pharmaceutical research due to its enhanced stability and potential for specific receptor targeting. It is primarily utilized by research institutions and pharmaceutical developers in the fields of endocrinology, oncology, and radiopharmaceutical development. The compound's unique structure makes it a valuable tool for studying hormone regulation and developing novel diagnostic or therapeutic agents.

Application

• Biochemical Research: Used as a stable, labeled analogue for studying somatostatin receptor (SSTR) binding, internalization, and signaling pathways.
• Pharmaceutical Development: Serves as a key intermediate or reference standard in the development of novel peptide-based therapeutics targeting neuroendocrine tumors and acromegaly.
• Radiopharmaceuticals: The selenium moiety provides a potential site for radiolabeling (e.g., with 75Se) for use in preclinical imaging (SPECT) and biodistribution studies.
• Proteomics & Peptide Chemistry: Employed in studies focusing on peptide stability, oxidation resistance, and the effects of selenocysteine incorporation on biological activity.
• Reference Standard: Acts as a high-purity certified reference material (CRM) for quality control in peptide synthesis and analytical method validation.

Basic Information

Item	Details
Product Name	Somatostatin, Seleno-Cys(3,14)-Trp(8)-
CAS No.	77201-60-6
Molecular Formula	C76H104N18O19S2Se2
Molecular Weight	~1877.0 g/mol
Synonyms	Somatostatin (selenium analog); [Selenocystine3,14, Tryptophan8]-Somatostatin-14; Selenium-labeled Somatostatin; Cyclo(Ala-Gly-CysSe-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-CysSe); SSTR ligand analog; SS-14 (Se-Cys3,14, Trp8); CAS 77201-60-6
EINECS	Contact for details

Quality Control

Our Somatostatin, Seleno-Cys(3,14)-Trp(8)- is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency. Each lot undergoes rigorous analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis. We provide comprehensive Certificates of Analysis (COA) detailing all specifications, ensuring compliance with research-grade standards. Custom synthesis and purification to meet specific project requirements are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by amino acid analysis)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Single Impurity (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.