Description

Enkephalin-Leu, Cyclo-N(Gamma)-Dinh-Butyryl- is a synthetic, cyclic peptide analog of the endogenous opioid peptide enkephalin. This compound is of significant interest for its potential role in neurobiological research and pharmaceutical development, particularly in studying opioid receptor interactions and pain modulation pathways. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in neuroscience, peptide chemistry, and drug discovery.

Application

• Neuroscience Research: Used as a biochemical tool to investigate the function and binding characteristics of delta and mu opioid receptors.
• Drug Discovery & Development: Serves as a key intermediate or reference standard in the development of novel analgesic and neuroprotective agents.
• Biochemical Assays: Employed in competitive binding assays, receptor autoradiography, and signal transduction studies to understand opioid system physiology.
• Peptide Chemistry Studies: Utilized in academic and industrial research to study structure-activity relationships (SAR) of cyclic peptide modifications.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in peptide synthesis and analysis.

Basic Information

Item	Details
Product Name	Enkephalin-Leu, Cyclo-N(Gamma)-Dinh-Butyryl-
CAS No.	77171-72-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Cyclo[Nγ-Dinh-butyryl-Leu-enkephalin]; Cyclo(Nγ-2,2-Dimethylsuccinyl) Leu-Enkephalin; c[Nγ-Dinh-Bu]LE; Cyclic Leu-Enkephalin analog; H-Tyr-Gly-Gly-Phe-Leu-c(Nγ-Dinh-Bu); Opioid peptide analog 77171-72-3; Cyclic enkephalin derivative
EINECS	Contact for details

Quality Control

Our Enkephalin-Leu, Cyclo-N(Gamma)-Dinh-Butyryl- is produced under stringent quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Our quality commitment supports reliable and reproducible results for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment. For long-term storage, consider desiccants or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Single Impurity (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.