Description

Fluorescein-Thyrotropin-Releasing Hormone is a synthetic, fluorescently labeled analog of the endogenous thyrotropin-releasing hormone (TRH). This compound is engineered for high-affinity binding and detection, serving as a critical tool in advanced biomedical research and diagnostic development. It is primarily utilized by pharmaceutical R&D teams, clinical diagnostic manufacturers, and academic researchers focused on neuroendocrinology and assay development.

Application

• Biomarker Research & Assay Development: Acts as a fluorescent tracer in competitive binding assays and fluorescence polarization (FP) assays to study TRH receptor interactions.
• Diagnostic Kit Manufacturing: Used as a key component in the development of sensitive immunoassays and test kits for thyroid and pituitary function disorders.
• High-Throughput Screening (HTS): Enables the screening of compound libraries for drug candidates targeting the TRH receptor pathway in pharmaceutical discovery.
• Cellular Imaging & Microscopy: Serves as a fluorescent probe for visualizing receptor localization and internalization dynamics in live-cell imaging studies.
• Neuroscience & Neuroendocrinology Studies: A vital tool for investigating the role of TRH in the central nervous system, including its effects on neurotransmitter release and neuronal excitability.

Basic Information

Product Name	Fluorescein-Thyrotropin-Releasing Hormone
CAS No.	77160-98-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Fluorescein-TRH; TRH-Fluorescein Conjugate; Fluorescein-labeled Thyrotropin-Releasing Hormone; Fluorescein-L-pyroglutamyl-L-histidyl-L-prolinamide; F-TRH; Fluoro-TRH; Thyroliberin-Fluorescein
EINECS	Contact for details

Quality Control

Our Fluorescein-Thyrotropin-Releasing Hormone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and diagnostic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and performance in relevant assays is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Orange to red solid
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Functional Activity (Binding Assay)	Conforms to reference

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.